Cutting Edge Science

One of the most unique aspects of the IMSMP is the seamless association with a state-of-the-art research facility. The Tisch MS Research Center of New York is an adjoining research center, currently investigating many different aspects of MS treatment and neuro-immunology. The stem cell research being performed at the Tisch MS Research is particularly intriguing. Such close proximity to cutting edge scientific breakthroughs provides hope to patients that we will continue to improve our MS treatments on the way to someday finding a cure.

Click on the logo to be directed to the Tisch MS Research website where you can find a listing of presentations, posters, abstracts and publications.



Current Clinical Trials at the IMSMP

Clinical trials help doctors and scientists test the safety and effectiveness of new or investigational medications and treatments. Many of the medications used at the IMSMP were tested in clinical trials to demonstrate their effectiveness in treating MS. Clinical trials have both potential risks and benefits for people who participate in them. Ineffective medication and possible side effects are potential risks, while receiving treatment otherwise unavailable and helping others with MS by contributing to medical research are among the potential benefits.

Below are some of the current clinical trials being conducted at the IMSMP. 

·         EFFECT Study

The IMSMP is a participating site in a multi-center study that investigates the effectiveness of disease modifying therapies (DMTs) on relapse remitting MS (RRMS) patients.  The study will follow RRMS patients treated with Tecfidera, Copaxone, Aubagio, or Gilenya to evaluate the relative effectiveness of these disease-modifying therapies.

·         iConquerMS™ (OPT-UP Study)

The IMSMP/Tisch MS Research is also involved in iConquerMS™, a project associated with the Accelerated Cure Project. iConquerMS™ empowers patients living with MS to independently enter their health data into a secure online database. This data will be analyzed in conjunction with that of thousands of other MS patients, allowing these individuals to contribute their data and ideas to the advancement of research. Visit

·         Intrathecal Methotrexate

We continue to further investigate the novel administration of this medication for MS, the protocol of which was created by Dr. Sadiq many years ago. Currently, we are systematically following patients to evaluate efficacy and safety, evaluating CSF biomarkers of treated patients, and reporting on the long-term safety of our patients who have continued on this treatment for over 3 years.

·         Memory and Multiple Sclerosis

The IMSMP is a participating site in a Kessler Foundation project that examines the effect of a memory retraining technique in patients with MS. 

·         Rituximab

We are continuing to investigate the use of Rituximab in MS in various projects. One such project is following patients who transition from Tysabri to Rituximab to further evaluate this medication’s safety and efficacy.

·         Plasmapheresis

The IMSMP is investigating the role of weekly plasmapheresis in patients with progressive forms of MS.  Plasmapheresis filters the blood of immunoglobulins, which may be causing damage to the central nervous system.

·         Stem Cell

In conjunction with the Tisch MS Research Center, we have an FDA-approved clinical trial that uses intrathecal autologous mesenchymal stem cells to with the goal of repairing the damage done in MS. Please see http://tischms.orgfor more information.

·         Benign MS

This study evaluates the features of patients with a benign MS disease course in an effort to better understand and define this clinical entity.

**The IMSMP also participates in a number of research projects in collaboration with the Tisch MS Research Center of NY. For more on these projects, see


For more information on any new clinical research please call (212) 265-8070